彭政

职称：校聘副研究员

学历/学位：研究生/博士

电话：15852838801

电子邮箱：zhengpeng@jiangnan.edu.cn

研究领域：

主要从事蛋白质工程和合成生物学领域的基础和应用研究，利用蛋白质工程和合成生物学技术实现功能蛋白（酶、肽和蛋白材料等）的定向设计及高效表达，开发功能蛋白在生物质资源增值、食品生物合成以及环境修复等领域的应用。近年来在领域权威期刊上发表SCI论文30余篇，申请/授权发明专利15件，主持国家自然科学基金、国家重点研发计划等纵向科研项目4项，入选江苏省卓越博士后计划（2022）。

国际国内学术组织任职情况:

Frontiers In Synthetic Biology, Review Editor (2023.11-)

学习工作经历

2023.12-至今，江南大学 未来食品科学中心/生物工程学院 校聘副研究员

2021.11-2023.11，江南大学 未来食品科学中心 博士后/助理研究员

2016.09-2021.01，江南大学 发酵工程专业 博士

一、论文（论著）发表情况

代表性论文：

1. 1. Yang Yuan, Zheng Peng*, Xinyi Jiang, Qi Zhu, Rongping Chen, Wenzhen Wang, Anxing Liu, Chengjian Wu, Chunhua Ma, Juan Zhang*. Metabolomics analysis of flavor differences in Shuixian (Camellia sinensis) tea from different production regions and their microbial associations. Food Chemistry, 2024, 443, 138542.

2. 2.  Zheng Peng, Shuai Luo, Dandan Zhao, Juan Zhang*. Biosynthetic melanin with excellent performance can be used for heavy metal adsorption. Journal of Cleaner Production, 2023, 385: 135655.

3. 3. Zheng Peng, Dandan Zhao, Jun Fang, Jian Chen and Juan Zhang*. Biosynthetic Amyloid Fibril CsgA–Fe₃O₄ Composites for Sustainable Removal of Heavy Metals from Water. Separation and Purification Technology, 2023, 329, 125191.

4. 4. Zheng Peng, Ran Wang, Xiaofeng Xia*, Juan Zhang*. Engineered acetaldehyde dehydrogenase for the efficient degradation of acetaldehyde. Journal of Environmental Management, 2023, 331: 117258.

5. 5. Zheng Peng, Mengni He, Xinyu Yang, Juan Zhang*. Discovery and characterization of a novel bacteriocin HA2-5 that strongly inhibits Propionibacterium acnes. Journal of Agricultural and Food Chemistry, 2023, 71(34), 12741–12748.

6. 6. Xiwen Chen^#, Zheng Peng^#*, Xiaomei Ji and Juan Zhang*. Reducing cellular autolysis of Bacillus subtilis to improve keratinase production. ACS Synthetic Biology, 2023, 12(10): 3106–3113.

7. 7. Zheng Peng, Zhoudi Miao, Xiaomei Ji, Guoqiang Zhang, Juan Zhang*. Engineering flexible loops to enhance thermal stability of keratinase for efficient keratin degradation. Science of the Total Environment, 2022, 845:157161.

8. 8. Zheng Peng, Xinzhe Mao, Wanmeng Mu, Guocheng Du, Jian Chen, Juan Zhang*. Modifying the Substrate Specificity of Keratinase for Industrial Dehairing to Replace Lime-Sulfide. ACS Sustainable Chemistry & Engineering, 2022, 10(20): 6863-6870.

9. 9. Jun Fang, Guanyu Zhou, Xiaomei Ji, Guoqiang Zhang, Zheng Peng*, Juan Zhang*. Design of 5'-UTR to enhance keratinase activity in Bacillus subtilis. Fermentation, 2022, 8(9), 426.

10. 10. Zheng Peng, Peng Xu, Yang Song, Guocheng Du, Juan Zhang* and Jian Chen*. Cysteine-mediated cyclic metabolism drives the microbial degradation of keratin. ACS Sustainable Chemistry & Engineering, 2021, 9(29): 9861-9870.

11. 11. Zheng Peng, Juan Zhang*, Yang Song, Rong Guo, Guocheng Du and Jian Chen*. Engineered pro-peptide enhances the catalytic activity of keratinase to improve the conversion ability of feather waste. Biotechnology and Bioengineering, 2021, 118(7): 2559-2571.

12. 12. Zheng Peng, Xinzhe Mao, Juan Zhang*, Guocheng Du and Jian Chen*. Biotransformation of keratin waste to amino acids and active peptides based on cell-free catalysis. Biotechnology for Biofuels, 2020, 13: 61.

13. 13. Zheng Peng, Juan Zhang*, Guocheng Du and Jian Chen*. Keratin Waste Recycling Based on Microbial Degradation: Mechanisms and Prospects. ACS Sustainable Chemistry & Engineering, 2019, 7(11): 9727-9736.

14. 14. Zheng Peng, Xinzhe Mao, Juan Zhang*, Guocheng Du and Jian Chen*. Effective biodegradation of chicken feather waste by co-cultivation of keratinase producing strains. Microbial Cell Factories, 2019, 18(1): 84.

15. 15. Xinyu Yang^#, Zheng Peng^#, Mengni He, Zhibin Li, Guihua Fu, Shaolei Li, Juan Zhang*. Screening, probiotic properties, and inhibition mechanism of a Lactobacillus antagonistic to Listeria monocytogenes. Science of The Total Environment, 2023, 906, 167587.

16. 16. Dandan Zhao^#, Zheng Peng^#, Jun Fang, Zhen Fang*, Juan Zhang*. Programmable and low-cost biohybrid membrane for efficient heavy metal removal from water. Separation and Purification Technology, 2023, 306, 122751.

17. 17. Xiaomei Ji^#, Zheng Peng^#, Jie Song, Guoqiang Zhang, and Juan Zhang*. Fusion of Substrate-Binding Domains Enhances the Catalytic Capacity of Keratinases and Promotes Enzymatic Conversion of Feather Waste. Journal of Agricultural and Food Chemistry, 2023, 71(30): 11579–11586.

18. 18. Xiaoxue Yang^#, Zheng Peng^#, Qi Zhu, Chengcong Chen, Jiheng Liu, Songtao Fu, Juan Zhang*. Analysis of Tieguanyin aged aroma compounds and their correlation with microbial communities based on multi-omics analysis. LWT - Food Science & Technology, 2023, 185: 115205.

     

    二、科研项目

19. 1. 国家自然科学基金青年项目(22208125) 2023.01-2025.12, 项目负责人

20. 2. 国家重点研发计划(2022YFD2101201) 2022.11-2027.10, 子课题负责人

21. 3. 江苏省自然科学基金青年项目(BK20221084) 2022.07-2025.06, 项目负责人

22. 4. 南平市资源化学产业科技创新联合资助项目(N2022Z003) 2023.01-2025.06, 项目负责人

23. 5. 国家重点研发计划(2022YFD2101402) 2022.11-2026.10, 参与

24. 6. 国家重点研发计划(2021YFA0911501) 2021.12-2026.11, 参与

三、科研成果及奖励

1. 1. 江苏省卓越博士后计划(2022ZB497) 江苏省人力资源和社会保障厅(2022年)

四、所获专利

1. 1. Zhang Juan, Peng Zheng, Chen Jian, Du Guocheng, Mao Xinzhe, Zhou Hengrui. Recombinant Bacillus Subtilis Engineered Bacterium Capable of Efficiently Expressing Keratinase. 专利号：US 11384394 B2

2. 2. 张娟，彭政，宋婕，陈坚，吉晓梅，堵国成，李江华. 一种具有底物选择性的角蛋白酶突变体及其应用. 专利号: 2023117300290

3. 3. 张娟，彭政，陈希文，陈坚，堵国成，李江华. 一种蛋白酶表达水平提高的底盘细胞. 专利号: 202310929472.4

4. 4. 张娟，彭政，吉晓梅，陈坚，堵国成，李江华. 一种利用角蛋白酶水解玉米黄粉醇溶蛋白的方法. 专利号: 2023107480117

5. 5. 张娟，彭政，宋婕，陈坚，堵国成，李江华，吉晓梅. 一种通过融合底物结合功能域提升水解能力的角蛋白酶突变体. 专利号: 2023100903337

6. 6. 张娟，彭政，吉晓梅，陈坚，堵国成，李江华. 一种无胶原蛋白水解活性的角蛋白酶突变体. 专利号: 202211539892.3

7. 7. 张娟，彭政，杨欣宇，陈坚，吴巧茵，堵国成，李江华. 一株可广谱抑制食品腐败菌的乳酸菌及其应用. 专利号: ZL 202210651979.3

8. 8. 张娟，彭政，陈坚，堵国成. 一种前导肽突变体及其在角蛋白酶生产中的应用. 专利号: ZL 201911153529.6

9. 9. 张娟，陈坚，彭政，堵国成，任春慧，范旭程. 一种利用角蛋白酶生产菌株高效降解羽毛的方法. 专利号: ZL 201711236769.3

以上资料更新时间截止：2024年1月